Run of Hope Seattle

Sunday, September 24th, 2023 Seattle, WA 98118 US

About Us

The Run of Hope Seattle is the joint effort of the Four Seasons Hotel Seattle and the Pediatric Brain Tumor Research Fund (PBTRF), a member of Seattle Children’s Guild Association since 2006. The mission of the PBTRF, is to raise money and awareness to advance pediatric brain tumor research. The Four Seasons Hotel Seattle has a long history of giving. Their corporate goal to raise awareness and funds for cancer research in the communities they serve, and the mission of the PBTRF has made the perfect partnership. Many members of the guild have experienced the pain and loss of this horrible disease first hand and have dedicated themselves to the discovery of better treatment options and outcomes than their children received. Please help us improve the odds for so many children!

  • Each year 3,500 more children—11.5 each day—are diagnosed with a pediatric brain tumor in the U.S.
  • 72 percent of children diagnosed with a brain tumor are younger than 15.2
  • Brain tumors are the deadliest form of childhood cancer. Some tumors, such as atypical teratoid/rhabdoid tumors and some brain stem gliomas, have survival rates of less than 20 percent.
  • Non-malignant/benign brain tumors can kill children if their location in the brain prevents surgical removal or other curative treatments.
  • There are 130 different types of brain tumors, making diagnosis and treatment very difficult.3
  • More than 612,000 people in the U. S. were living with a diagnosis of a primary brain or central nervous system tumor in the United States in 2004.4 Of this number, approximately 28,000 were children with a primary brain tumor.5
  • Pediatric brain tumors are not like those in adults. Children’s brain tumors require specific research and different treatments.
  • Even though survival rates for some childhood brain tumors have increased over the past 30 years, survivors often suffer from lifelong side effects of treatments such as surgery, radiation and chemotherapy.
  • Brain tumors are located in children’s control center of thought, emotion and movement, often resulting in long-term side effects. Survivors can have physical, learning and emotional challenges that will limit the quality of their lives into adulthood.
  • Research that focuses specifically on pediatric brain tumors is crucial to saving children’s lives and improving survivors’ quality of life.



1. Central Brain Tumor Registry of the United States (CBTRUS) Statistical Report, Feb. 2012

2. Ibid.

3. WHO Classification of Tumours of the Central Nervous System - World Health Organization . 4th Edition, 2007

4. Porter KR, McCarthy BJ, Freels S, Kim Y, Davis FG. “Prevalence Estimates for Primary Brain Tumors in the US by Age, Gender, Behavior, and Histology”,  Neuro-Oncology, 12(6): 520 527, 2010.

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